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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCN3
All Species:
22.42
Human Site:
T486
Identified Species:
70.48
UniProt:
Q9P1Z3
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P1Z3
NP_065948.1
774
86032
T486
G
A
R
D
T
R
L
T
D
G
S
Y
F
G
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115891
777
86237
T488
G
A
R
D
T
R
L
T
D
G
S
Y
F
G
E
Dog
Lupus familis
XP_547548
782
86616
T488
G
A
R
D
T
R
L
T
D
G
S
Y
F
G
E
Cat
Felis silvestris
Mouse
Mus musculus
O88705
779
86623
T485
G
A
R
D
T
R
L
T
D
G
S
Y
F
G
E
Rat
Rattus norvegicus
Q9JKA8
780
86790
T485
G
A
R
D
T
R
L
T
D
G
S
Y
F
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425050
1188
129247
A627
G
N
K
E
T
K
L
A
D
G
S
Y
F
G
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686078
1078
119210
S614
G
N
K
E
T
K
L
S
D
G
S
Y
F
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24278
665
75805
L404
A
L
D
E
E
R
V
L
A
A
L
P
D
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.6
94.6
N.A.
94.7
94
N.A.
N.A.
45.5
N.A.
52
N.A.
24.8
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
98.3
95.2
N.A.
95.5
95.1
N.A.
N.A.
53.6
N.A.
60
N.A.
42.1
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
66.6
N.A.
66.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
86.6
N.A.
93.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
63
0
0
0
0
0
13
13
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
63
0
0
0
0
88
0
0
0
13
0
0
% D
% Glu:
0
0
0
38
13
0
0
0
0
0
0
0
0
0
88
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
88
0
0
% F
% Gly:
88
0
0
0
0
0
0
0
0
88
0
0
0
88
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
25
0
0
25
0
0
0
0
0
0
0
13
0
% K
% Leu:
0
13
0
0
0
0
88
13
0
0
13
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
63
0
0
75
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
13
0
0
88
0
0
0
0
% S
% Thr:
0
0
0
0
88
0
0
63
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
88
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _